WHAT CAUSES ALZHEIMER’S DISEASE? 

Alzheimer’s disease is a progressive brain disorder that leads to memory loss, cognitive decline, and difficulty with daily tasks. The exact cause isn’t fully understood, but scientists have identified several key factors that contribute to its development:

1. Buildup of Toxic Proteins in the Brain

🔹 Beta-Amyloid Plaques

• Sticky protein fragments that clump together between brain cells.
• Disrupts communication between neurons and triggers inflammation.

🔹 Tau Tangles

• A protein called tau becomes twisted inside brain cells.
• Blocks nutrient transport and leads to cell death.

2. Brain Cell Damage & Shrinkage

• Brain cells (neurons) die, causing the brain to shrink (atrophy).
• The hippocampus (memory center) is one of the first areas affected.

3. Inflammation & Immune System Problems

• Overactive immune responses attack healthy brain cells.
• Chronic brain inflammation speeds up damage.

4. Reduced Blood Flow & Energy Supply

• Poor circulation reduces oxygen and nutrients to the brain.
• Mitochondria (brain's energy powerhouses) become less efficient.

5. Genetic Factors 

• The APOE4 gene increases the risk of Alzheimer’s.
• Other rare genetic mutations can cause early-onset Alzheimer’s (before age 65).

6. Lifestyle & Environmental Factors 

• Unhealthy diet (high in processed foods, trans fats)
• Lack of exercise (reduces blood flow to the brain)
• Poor sleep (deep sleep clears toxic proteins)
• Chronic stress (increases brain inflammation)
• Social isolation (less mental stimulation = higher risk)

7. Other Health Conditions 

• Diabetes & Insulin Resistance (linked to "Type 3 Diabetes")
• High blood pressure & heart disease (affect brain circulation)
• Obesity & metabolic syndrome

Can Alzheimer’s Be Prevented?

✅ Eat a brain-healthy diet (Mediterranean diet, Omega-3s)
✅ Exercise regularly (walking, strength training, cardio)
✅ Improve sleep (7–9 hours of deep sleep)
✅ Keep learning & stay social (stimulates new brain connections)
✅ Manage stress (meditation, relaxation techniques)