Tuesday, April 8, 2025

 WHAT ARE THE SUPPLEMENTS THAT CAN DELAY AGING?

There’s no magic pill to stop aging, but some supplements show promise in slowing down aspects of the aging process or improving health span (how long you stay healthy). Here’s a breakdown of supplements with the most evidence behind them:

🧬 Cellular Aging & DNA Protection

  1. NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside)
    • Boosts NAD+ levels, important for energy production and DNA repair.
    • Shown to improve mitochondrial function and possibly slow aging in mice.
    • Human data is early but promising.
  2. Resveratrol
    • Found in red wine and grapes.
    • Activates sirtuins (proteins involved in longevity).
    • Often taken with NMN/NR for synergy.
  3. Fisetin
    • Plant flavonoid with senolytic properties (clears "zombie cells").
    • Shown in animal studies to reduce inflammation and improve lifespan.
  4. Quercetin + Dasatinib
    • Another senolytic combo studied for removing senescent cells.
    • Mostly experimental and used in controlled settings.

🧠 Brain Health & Cognitive Longevity

  1. Lion’s Mane Mushroom
    • Stimulates nerve growth factor (NGF), supports neurogenesis.
    • May help memory, mood, and focus over time.
  2. Omega-3 (EPA/DHA)
    • Reduces brain inflammation, supports cognitive function.
    • Good for heart and joints, too.
  3. Phosphatidylserine
    • A phospholipid that supports brain cell membranes.
    • May help with memory and cognition in older adults.

🛡️ Inflammation & Oxidative Stress

  1. Curcumin (with piperine)
    • Potent anti-inflammatory and antioxidant.
    • May support joint health, brain health, and immune function.
  2. CoQ10 (Ubiquinol)
    • Supports mitochondrial function and energy.
    • Especially beneficial if you're taking statins.
  3. Astaxanthin
    • A powerful antioxidant.
    • Supports skin, eyes, and cardiovascular health.

🦴 Hormonal Support & Longevity Pathways

  1. Vitamin D + K2
    • Supports immune function, bone health, and may reduce mortality risk.
    • Most people are low in D, especially in winter.
  2. Magnesium (especially glycinate or threonate)
    • Crucial for over 300 enzymatic processes.
    • Helps with sleep, muscle recovery, and brain function.
  3. Zinc + Selenium
    • Immune support, thyroid function, and DNA repair.

⚠️ Notes

  • Always talk to your doctor—especially if you're on medications.
  • Supplements ≠ substitutes for sleep, exercise, healthy diet, stress management.
  • Quality matters: go for third-party tested brands.


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